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Senior Statistical Modeler

Synthorx

Synthorx

Swiftwater, PA, USA
Posted on Tuesday, June 4, 2024

About the Job
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.​

Summary of Purpose

The Senior Statistical Modeler is responsible for enabling model informed vaccine clinical development and will develop and apply tools and algorithms using statistical/machine-learning and mechanistic models for integrated model-based analysis of data spanning the responsibilities of Global Biostatistics in Vaccine Clinical Research and Development.

Key accountabilities

  • 40% of the time - Clinical Trials simulation, including in silico modeling, leveraging historical Clinical Trials Data and Real World Evidence plus publications

  • 25% of the time - Translational & Disease Modeling, leveraging pre-clinical, non-clinical, and clinical data

  • 20% of the time - Model the relationship between endpoints, understanding and defining new relevant endpoints in vaccines development

  • 15% of the time - Leverage predictive modelling (e.g. correlate of risk, correlate of protection) during and after the conduct of clinical trials

Context of the job/ Major challenges

An ideal Statistical Modeler is an analytical and creative thinker who is not intimidated by roadblocks and challenges. They understand how to successfully evaluate problems and develop appropriate solutions. Successful Statistical Modelers can also be counted on to perform well under pressure, possessing great focus while completing projects efficiently. They should be able to work well as part of a team, but also carry responsibility for their own work. Statistical Modelers also need to be able to work on multiple projects at a time, with the ability to quickly understand and incorporate new technologies. They will use Historical Clinical Trials data, Real World Data, and literature with Statistical & Mathematical Modeling, leveraging mechanistic & statistical models together with AI/ML to enhance Vaccine Development at Sanofi.

Dimension/Scope

The Statistical Modeler is responsible for supporting GBS teams through all project phases including knowledge transition. They will analyze data-related system integration challenges and propose and implement appropriate solutions. Some travel and interaction with external experts are expected.

Education

Ph.D. in Engineering, Data Science, Computer Science, Statistics, Mathematics or related discipline is required.

Required Experience

  • R & SAS programming experience

  • General understanding of data collection processes and data quality

  • Knowledge of the mathematical foundations of statistical inference and forecasting.

  • Demonstrated expertise in the use of:

    • statistical/machine learning as well as mechanistic models.

    • Bayesian statistics

  • Ability to clearly communicate complex technical ideas, regardless of the technical capacity of the audience.

  • Strong inter-personal skills and ability to work as part of a team.

  • Ability to quickly learn and adapt modeling methods from case studies or other approaches (e.g., publication).

  • Experience in vaccine research and development is desirable but not required.

Sanofi Core Competencies

  • Act for Change & Innovation

  • Commit to Customers

  • Cooperate Transversally

  • Strive of Results

  • Thinking Strategically

  • Make Decisions

  • Lead People

  • Develop People

Job Specific Competencies

  • Rigour, Organization skills

  • Customer Orientation & Influencing skills

  • Communication and Interpersonal skills

  • Ability to work in a team

  • Computer skills (SAS, R, Office,…)

  • Very Good level of English (written and spoken)

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!