Sr. Research Associate – Delivery & formulation development

We are seeking a highly motivated and scientifically rigorous individual to join the Delivery and formulation development team as a Sr. RA. The position will focus on developing novel lipid nanoparticle (LNP) formulations for mRNA delivery.

Responsibilities

• Prepare formulations and perform characterization assays /data analysis with focus on in vivo studies, drug carrier design/development, assay development etc.

• Establish stability profile and advance understanding of stability of LNP drug products for storage and administration of drug products.

• Support vaccine formulation development activities.

• Contribute to the development & writing/reviewing analytical method protocols.

• Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.

Qualifications

• B.S./M.S. in Chemistry/Physical Chemistry/Biochemistry/ Chemical Engineering/Bioengineering/Pharmaceutical Science

• 3+ years with BS or 2+ years with MS of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization

• Direct experience with messenger RNA encapsulation/quantification/characterization/handling is preferred

• Understanding and success in implementation of RNA-related analytics (Ribogreen, gel electrophoresis, capillary electrophoresis, etc.) is desired

• Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred

• Experience in developing LNP formulations for Gene/ cell immunotherapy would be advantageous

• Works collaboratively within group as well as within interdisciplinary teams

• Manages time effectively demonstrating ability to perform multiple projects at one time

• Desire to work in a fast-paced environment

• Excellent organizational and communication skills

• Strong analytical and problem-solving skills

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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