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Senior Research Associate, Genomic Medicine Unit - BioAnalytics

Synthorx

Synthorx

Data Science
Waltham, MA, USA
Posted on Saturday, September 16, 2023

Position Overview/Department Description

The Genomic Medicine Unit (GMU), a part of Sanofi’s CMC Development organization, is dedicated to the establishment of best-in-class platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lipid nanoparticles, and cell therapy products. The BioAnalytics Characterization group uses advanced analytical techniques for in-depth structural and functional characterization of gene therapy/cell therapy products in support of drug development, from pre-candidate selection through commercialization. We are seeking a motivated Senior Research Associate to join our BioAnalytics Characterization group in the Genomic Medicine Unit within Sanofi. This role is an opportunity to gain experience in the rapidly growing modality of genomic medicine (including viral gene therapies, lipid nanoparticles, and cellular therapies).

Responsibilities:

  • Perform analytical characterization techniques such as LC-MS, SV-AUC, SEC/FFF- MALS & NTA.

  • Independently designs and performs experiments and data analysis.

  • Learns to initiate and develop work plans to ensure the timely completion of several sets of experiments.

  • Performs complex analytical procedures using established techniques.

  • Interprets and reports results in oral and written formats.

  • Maintain chemical inventory, MSDS and instruments.

  • Perform data backup and transfer.

Basic Qualifications:

  • Master’s Degree in a relevant discipline, or a Bachelor’s Degree in a relevant discipline and >2 years of relevant experience.

  • The candidate should be self-motivated, well-organized, attentive to detail and a good oral and written communicator. The candidate must be able to work well in a team environment and have good problem-solving skills.

  • The candidate should be proficient in Microsoft office including Word and Excel.

  • Experience characterizing proteins, viral vectors or cell therapies using multiple tools and orthogonal data to build and study protein and viral degradation and behavior.

Preferred Qualifications:

  • Experience in LC-MS analysis such as intact protein and peptide mapping.

  • Experience in the characterization of gene-therapy (AAV & LNPs)/cell therapy products and deep understanding of the products.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Overview

From Research and Development to Sales and Marketing, Sanofi offers a wide range of possibilities. Discover our open positions and become a health journey partner.

Success Profile

  • Do you have what it takes for a successful career with Sanofi?

  • Courageous, Results-driven, Proactive, Problem-solver, Leadership, Team player

Culture: Play to Win

  • Growth

  • Innovation

  • Efficiency and Collaboration

Benefits:

  • Health & Wellness

  • Comprehensive coverage including medical, dental, vision, and health and wellness programs.

Financial

Sanofi wants to ensure employees are equipped for financial health, Sanofi provides a competitive 401K Match program and Financial Well-Being Tools and Programs.

Culture

At Sanofi, we demonstrate our commitment to inclusion and diversity through Culture groups and programs. There are many ways to make a difference and connect with other Sanofi employees: including ERG groups and 2 PAID days off to Volunteer.

Work/Life Balance

Sanofi provides significant Work/Life benefits to help you excel beyond the workday. Including Workplace Flexibility through part‑time, remote work, flex‑time and job share options.

“At Sanofi, we are guided by a deep appreciation and understanding of what it means to live with a rare blood disorder, and we learn by listening to the community – patients, caregivers, physicians, and other healthcare professionals.”

Shannon Resetich

US Head Rare Diseases & Blood Disorder

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.