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Purification Development Research Associate

Synthorx

Synthorx

Framingham, MA, USA
Posted on Wednesday, November 29, 2023

Department Description:

Mammalian Purification Process Development, part of the Sanofi R&D CMC organization, is responsible for development, scale-up, transfer, and characterization of purification processes for clinical and commercial manufacturing of therapeutic proteins from the mammalian production platform. In addition, the department develops next-generation bioprocessing and process development technologies such as integrated and continuous bioprocessing, high throughput process development, and mechanistic modeling of bioprocesses. The department also works to support a global purification network and update our purification platform.

Job Responsibilities:

We are looking for candidates for the position of Research Associate. This individual will join a dynamic and motivated team to develop downstream purification processes in support of early and late stage drug development programs. In addition, the Research Associate will support the tech transfer of the developed process into the clinical manufacturing team or Industrial Affairs organization, while ensuring the highest standards of safety, environmental, and regulatory compliance are maintained in the workplace. Responsibilities include:

  • Work with supervisor to design, plan and conduct purification experiments, including data analysis, using high throughput purification models and benchtop and/or pilot scale chromatography and filtration systems

  • Document experiment results in technical reports, and present results at departmental meetings

  • Work with supervisor to evaluate new technologies to increase purification process understanding, performance, and/or process robustness

  • Develop, maintain, and demonstrate knowledge of principles, theories, and techniques in area of responsibility

  • Stay abreast of relevant new technologies and published literature, including attending technical forums

  • Maintain good communication and collaboration with colleagues in Purification Process Development, as well as other departments

Basic Qualifications

  • Bachelor's degree in Chemical Engineering, Biochemical Engineering, Biochemistry or related discipline

Preferred Qualifications:

  • Laboratory experience, in either an academic or industrial setting

  • Logical and critical thinking skills, as well as innovative problem solving

  • Ability to work independently and also function in a matrix/collaborative/team oriented environment

  • An understanding of scientific principles underlying and/or experience with purification technologies and operations

  • Excellent organization and written and oral presentation skills

  • High level of scientific curiosity

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.