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POSTDOC - Scientist

Synthorx

Synthorx

Vitry-sur-Seine, France
Posted on Monday, February 12, 2024

Description de l'emploi

Postdoctoral fellowship - Immuno-Oncology - deciphering myeloid cell heterogeneity in solid tumors (All Gender)

Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.

CONTEXT

Sanofi and Gustave Roussy (Europe's leading cancer center) are recruiting a Postdoctoral Researcher to join our group Research Unit 1015, headed by Dr. L. ZITVOGEL, as part of Florent GINHOUX's team working on “Targeting myeloid cell heterogeneity” The position is for a 36-month fixed-term contract.

As a full-time Postdoctoral Researcher in the Ginhoux Laboratory, the candidate will work on tumor macrophage heterogeneity in treatment resistant tumors/metastasis. Using advanced technologies (e.g., single-cell RNAseq, ATAC-seq, spatial transcriptomics, etc.) associated with spectral cytometry and the use of tool compounds, this study aims to better characterize and manipulate tumor macrophage heterogeneity in health and disease. Experience in bioinformatics, bench work and human sample manipulation is required.

The project will focus on tumors and metastasis in different difficult to treat cancer indications, including but not limited to lung and GI cancers. This project will necessitate to interact with other teams working in Paris. Together, the goal is to develop innovative approaches of treatment as well as fundamental understanding of tumor associated macrophages.

KEY RESPONSIBILITIES

  • Generate and analyze data in collaboration with scientists.
  • Work closely with other postdoctoral researchers and students to advise on analysis and experiments.
  • A key part of this responsibility will be to incorporate pedagogical best practices to build a highly valued set of training material.

This is a flexible job that provides opportunities for research and extensive collaboration in the context of a strong intellectual environment with good work-life balance. The Ginhoux group lies at the intersection of scientific research and large-scale computational analysis and works with many research groups. We are thus looking for someone who has a keen ability for picking up new knowledge and enjoys working on a wide variety of projects across a range of methods.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, gender identity, sexual orientation, pregnancy, or any other characteristic protected by law.

PROFILE

Basic Qualifications

• PhD in immunology.

• Proficient in human sample handling, molecular biology, flow cytometry and bench work.

• Proficient in R.

Additional Qualifications and Skills

  • Knowledge in Linux shell scripting, high performance computing, and workflow management systems such as Snakemake or Nextflow
  • Excellent written and verbal communication skills, including the ability to document methods and results clearly and concisely for tutorials and manuscripts
  • Ability to interact well with a broad constituency including students, postdoctoral fellows, faculty, and research staff.

CONTACT

We are seeking talented and passionate people to join our team. If you are interested in joining us, please send an email to aymeric.silvin@gustaveroussy.fr and include your CV and contact information for references.

Aymeric SILVIN Chercheur

Bâtiment de Médecine Moléculaire

114 rue Edouard Vaillant

94800 VILLEJUIF

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