Companies you’ll love to work for

companies
Jobs

Head of Production

Synthorx

Synthorx

Product
Singapore
Posted on Jan 20, 2026
Internal Job Description

Job title: Head of Production

  • Location: Singapore

  • Grade: L3-2

  • Hiring Manager: Site head Singapore

Responsible for production of intermediates and active pharmaceutical ingredients and operation of the related environmental control or ancillary systems, ensuring company objectives and targets are met with respect to output, quality, environment, health and safety.

REPORTING RELATIONSHIP

1. Reporting to the Site Director, the jobholder will be a member of the Site Leadership Team (SLT).

2. Direct reporting to the jobholder are :

a. The Plant operations executives who are members of production leadership team

b. Shift supervisors managing chemical technicians.

c. The production scheduler who is in charge of the daily production planning of the two plants.

3. Indirect Reporting Job Holder are:

a. Jurong APU core team members from Engineering, Quality, Supply Chain, OpsEx and

FUNCTIONAL LEVEL ACCOUNTABILITIES

  • Participate as a key member of the site +QDCI team by proactively engaging cross functionally to achieve site goals and priorities. Ensure that reporting staff understand the shared accountabilities at department +QDCI team for goals and priorities

  • Deliver production planning and production capacities assessments with appropriate tools for budget, long-range planning purposes and according to specific management requests.

  • Develop and maintain performance metrics for site manufacturing activities and communicate department progress to management and staff not limit to the following :

a. Schedule Adherence

b. Yields and cycle time

c. Productivity & OEE performance

d. Monthly expenses align with budget

e. Operational safety, hygiene and environmental impact at the workshops

4. Support and facilitate the implementation of the Sanofi Manufacturing System and associated performance improvement initiatives at site level

  • Lead and coordinate the required resources to develop and execute the near and long-term site strategy to maximize manufacturing capacity and deliver manufacturing excellence

  • Continually advise and ensure completion of improvement projects on all aspects of process engineering and chemistry in coordination with Process and Technology team

  • Partner EHS team to implement sustainable strategy on waste management

  • To evaluate any new opportunities for additional activities or performance improvements and estimate the potential gains.

SITE LEVEL ACCOUNTABILITIES

9. Drive and implement appropriate directions that foster positive safety behaviour and wellbeing of the employees in Production. Ensure compliance of company Life Saving Rules and being proactive in identifying, addressing and resolving issues in a timely manner

10. Manage the production facilities to manufacture active pharmaceutical ingredients on schedule and meeting all regulatory, quality and supply chain requirements

11. Champions and drives continuous improvement in the department with close coordination with other departments and contribute to the company’s priorities in environment, safety, quality and customer service level.

12. Ensure appropriate course of actions are taken for the manufacturing process and the scientific knowledge to meet safety, quality requirements and optimize yield and performance.

13. Ensure timely implementation of CAPA and closure of all critical, major, and minor deviations

14. Responsible for positive outcome of GMP and HSE regulatory inspection, self-inspection and other audits

15. Ensure close collaboration with other site departments to carry out projects’ implementation

16. Author, review and verify that adequate and appropriate procedural documents are current and available. Proper records are maintained and updated for the manufacturing process

17. Responsible for effective operation of the workshops emission control systems to prevent regulatory citation

18. Prepare annual departmental budget in collaboration with finance, review costs and contribute to improvements for operational effectiveness

19. Develop and implement training programs, conduct training and ensure training records are maintained

20. Plan succession strategy at all levels through talent acquisition, performance management, providing opportunity for high performers, communication of expectation and mentor department staff, emphasizing functional and cross-functional teamwork with effective communication

21. Perform any other function related duties as assigned and directed

Comply with all local and global policies and defined procedures and regulations.

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!