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HEOR Modeling Manager

Synthorx

Synthorx

Barcelona, Spain
Posted on Feb 10, 2026

HEOR Modeling Manager

  • Location: Barcelona, Spain

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About the job

As an HEOR Modeling Manager you will provide functional and operational directions to internalize HEOR modeling (Cost-effectiveness analysis, budget impact analysis, Global model support, early health economic models, model adaptation, scenario analysis etc.) processes in partnership with Global HEVA team and HEVA Business Partners.

People:

  • Collaborate with HEVA modeling leads to consult with Value and Access and HEVA Business Partners to determine model requirements

  • Collaborate with colleagues from HEVA, medical affairs, and commercial product teams to executive analysis of pre-existing model/scenario to investigate research queries

  • Collaborate with Global HEVA modeling leads to liaise external vendors supporting any modeling work and will be accountable for any development and validation required

  • Interact with pricing, external vendors

  • Lead team of HEVA modelers (Associate to Associate Manager) in health economic model development. Coach and mentor team members

Performance:

  • Provide inputs to the strategic development and use of industry leading predictive and economic models to enhance our understanding of disease and to quantify and communicate the value of our products to patients, providers, and payers

  • The Manager (HEOR modeling) will be responsible for developing health economic models like cost-effectiveness models, budget impact models, run scenario analysis

  • Ensure timely availability of complex and/or simple clinical, economic models that meet the need of payers by collaborating with internal/external stakeholders

  • Participate in conceptualization of advanced model design

  • Work on methodological aspect of modeling

  • Collaborate with Global HEVA modeling teams on economic platforms workstreams related to allocated projects

  • Get involved in analyzing prospectively collected health economic data or inclusion in model

  • Support countries for local HTA submissions

  • Develop and maintain expertise across therapeutic area

Process:

  • Support development of HEOR modeling processes in partnership with HEOR modeling leads/managers

  • Contribute in overall quality enhancement by ensuring high scientific standards for the output produced by team

  • Ensure all the HE modeling deliverables are delivered as per agreed time and standard

About you

Technical skills: Advanced level training/experience in developing health economic models (CEA, BIM, survival analysis, patient level simulation), hands on experience of working with Excel VBA, familiarity with R, R-shiny

Soft skills: Stakeholder management; communication skills; people management; and ability to influence and negotiate

Languages: Excellent knowledge of English language (spoken and written)

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